久久久精品欧美一区二区三区,国产欧美久久久精品影院,亚洲AV福利天堂一区二区三亚洲欧洲日韩国产AⅤ在线,亚洲成av人在线视,四虎国产精品永久地址99自拍三区一级国产片,亚洲男人的天堂久久无在线观看免费黄视频,亚洲一级特黄大片在线播放,国产成人精品区在线观看

Affinity Chromatography Resin
Home > Technology > Chromatography Resin > Affinity Chromatography Resin > Antibody Purification Resin

Antibody Purification Resin


Affinity chromatography resins are mainly used for the capture and purification of monoclonal antibodies/bispecific antibodies, fusion proteins or other protein molecules with specific binding sites. Considering different purification requirements, Bogen (A Duoning company) provides affinity chromatography media based on polymer hard gel matrix (three series of HP/CP/GP according to pore size) and agarose soft gel matrix.

 

The hard gel chromatography resin developed by Bogen uses high-strength hydrophilic polyacrylate beads as matrix, and adopts unique flexible hydrophilic modification technology to further reduce non-specific adsorption caused by hydrophobic micro surface of hard gel chromatography resins , which helps to improve protein recovery and robustness of purification process.

 

Bogen has developed industry-leading multi-scale micro-nano structure control technology, which can realize the precise regulation of the pore size of the chromatography resin. Based on the size of protein molecular weight, we can provide chromatography resins with different pore sizes:

 

?   HP series affinity chromatography resins: suitable for molecules with MW <200 KD

?   CP series affinity chromatography resins: suitable for molecules with MW 100 KD-300 KD

?   GP series affinity chromatography resins: suitable for molecules or viruses/vaccines with MW > 150 KD

 

Antibody Purification Resin

 

Antibody Purification Resin (GP-ProA) is alkali-resistant affinity chromatography resin developed for purification of monoclonal antibody/bispecific antibody, separating antibody of interest from the impurities through the specific binding between ProA ligand and antibody. This product uses super-macro-porous polyacrylate beads as matrix and alkali-resistant recombinant ProA as binding ligand, featuring high flow rate, low back pressure, and high stability, which are obvious advantages in commercial manufacturing of antibody-based biopharmaceuticals.

 

Antibody Purification Resin (ProG) is affinity chromatography resin specially developed for purification of antibodies from ascites and serum. This product uses agarose-based soft gel beads as matrix and r-ProG as binding ligand, achieving high binding capacity and long-life cycle.

 

Product Features

Product

Antibody purification resin (GP-ProA)

Antibody Purification resin (ProG)

Matrix

Super macroporous polyacrylate hard gel

Agarose soft gel

Ligand

r-Protein A

r-Protein G

Average particle size

70μm

90μm

Ligand density

10mg/mL

5mg/mL

Dynamic capacity

≥40mg/mL

≥30mg/mL

Max flowrate

1500 cm/h

600 cm/h

Max Pressure

1 Mpa

0.3 Mpa

Storage

2-8°C (20% ethanol)

2-8 (20% ethanol)

Applicable range

Monoclonal/bispecific antibodies, Fc fusion protein

Human, mouse, bovine, horse derived IgG

PH Stability

Can withstand 0.5M NaOH cleaning (It is recommended that the cleaning time should not exceed 20 minutes)

3-12 (long term)

2-13 (short term)

 

Case Study

 

Chromogram of mAb purification process by GP-ProA

Antibody Purification Resin

Column size: 0.78cm ID x 10cm

Flowrate: 1 mL/min

Detection wavelength: 280nm

Sample: Clarified mAb cell culture medium

Elution purity: 96.65%

Elution recover rate: 92.51%

Concentration factor: 4-10 x


Ordering Information

 

GP series

Product Name

Part No.

Specification

Product Name

Part No.

Specification

Antibody purification resin (GP-ProG)

BG16-3110-02

50mL

Antibody purification resin (GP-ProA)

BG18-3110-02

50mL

BG16-3110-04

500mL

BG18-3110-04

500mL

BG16-3110-05

1L

BG18-3110-05

1L

BG16-3110-07

10L

BG18-3110-07

10L

BG16-3110-08

20L

BG18-3110-08

20L

 

Agarose series

Product Name

Part No.

Specification

Product Name

Part No.

Specification

Antibody purification resin (ProG)

BG16-0010-02

50mL

Antibody purification resin (ProA)

BG18-0010-02

50mL

BG16-0010-04

500mL

BG18-0010-04

500mL

BG16-0010-05

1L

BG18-0010-05

1L

BG16-0010-07

10L

BG18-0010-07

10L

BG16-0010-08

20L

BG18-0010-08

20L

 

Prepacked column

Product Name

Specification

Applicable   Molecular Weight

Capacity

Max Pressure

Max Flow rate

Application/Feature

Antibody purification column (ProG)

5mL

10mL

≤200KD

30mg/mL

0.3MPa

600cm/h

Used to purify antibodies from ascites and serum

Antibody purification column (GP-ProA)

5mL

10mL

≥150KD

40mg/mL

1MPa

1000cm/h

Used for scale-up study of antibody purification process, high flow rate, low back pressure, high stability

 

 


Relevant Documents

Contact Us
  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
Message

Copyright ? Shanghai Duoning Biotechnology Co., Ltd. All Rights Reserved Sitemap | Technical Support: Reanod

WeChat
WeChat

Message-

Duoning Biotechnology

+86 021 6434 0155

性欧美精品一区二区三区在线播放| 免费A级毛片无码A∨免费软件| 久久av无码午夜鲁丝片| 亚洲欧美日本国产高清| AV精品一区二区三区| 亚洲中国久久精品无码 | 国产精品无码素人福利免费| 亚洲AV无码一区二区一二区| 中文字幕亚洲一区一区| 四虎影视成人永久免费观看视频| 亚洲性无码一区二区三区| 国产黄大片在线观看画质优化| 久久精品人人槡人妻人人玩AV| 亚洲成av人在线视| 亚洲国产综合精品2020| 一级特黄高清aaaa大片| 国产一区二区波多野结衣婷婷| 亚洲精品tv久久久久久久久| 亚洲国产综合精品2020| 久久天天躁狠狠躁夜夜躁2O2O| 久久精品亚洲乱码伦伦中文| 无码人妻毛片丰满熟妇区毛片| 熟妇久久无码人妻av蜜臀| 18禁美女黄网站色大片免费观看| 国产高潮呻吟久久| 国产chinese男男gay视频网| 国产在线拍揄自揄拍视频| 制服诱惑中文字幕一区不卡| 日本熟妇一区二区三区在线视频| 日韩精品中文字幕一区三区| 欧美性猛交一区二区三区精品| 国产对白老熟女进行播放| 亚洲伊人成色综合国产高清精品毛片| 人妻仑刮八A级毛片免费看| 中文精品久久久久国产网址| 青青人妖无遮挡久久99国产一区二区三区亚洲一区影院午夜福利| 久久夜色精品国产噜噜麻豆| 歐美日本一区二区三区在| 国产欧美精品在线一区二区三区| 日韩精品区一区二免费| 久久国产劲暴∨内射新川|