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Bulk Fill Systems
Home > Technology > Fluid Management Solutions > Bulk Fill Systems > DuoFill Single-Use Bulk Filling System

DuoFill Single-Use Bulk Filling System


As the pharmaceutical industry develops, manufacturing scales and the number of batches are increasing. Traditional manual methods can no longer meet the current requirements for bulk filling. The fully automated bulk filling system can achieve rapid filling and audit-matching data recording. It solves the problem of quickly performing aseptic bulk filling in clean rooms and provides a better solution for subsequent product data audit tracking.

 

Product Benefits:

?   Single-use and fully closed design. No valve, less hold up;

?   Gravimetric method and Flow Rate method supported. Filling accuracy: ±1%;

?   Flexible recipe editing and parameter setting. The system can automatically recognize weight gain or weight loss filling modes after the parameters are set;

?   Built-in automatic filtration program: Supports constant flow/constant pressure filtration and sterile filtration operations;

?   Meet the requirements for research, pilot and commercial scales: suitable for freeze-thaw bags, storage bags, or bottles. All parts of the system can be quickly reassembled;

?   Compact footprint: Can be placed on a desktop and used within standard laminar flow hoods or ultra-clean workbenches;

?   The system can be integrated with mixers, weighing system, and power system. Which enhances the automation and intelligence of the filling procedures;

?   12 reserved sensor ports and 2 network interfaces: Easily integrate on-site instruments or upload data;

?   The control system complies with GMP requirements and responds quickly, with a startup time less than 1 minute.

 

System Applications:

?   Bulk filling

?   Intermediate filling

?   Cell culture media filling

?   Buffer filling

 

Function Modules:

?   Sterile Filtration

?   Exhausting and Purging

?   Pressure / Flow / Weight Monitoring

?   Data Integrity

?   External Devices Communication and Interaction


Main Controller

DuoFill Single-Use Bulk Filling System

 

Interconnectable Modules

DuoFill Single-Use Bulk Filling System

Module Connection Interface:

DuoFill Single-Use Bulk Filling System

 

Main Specifications:

Item

Description

Enclosure material

ABS

Protection rating

IP54

Controller dimensions

545*420*500 (L*W*H)/mm

Single container volume

≥100 mL

Filling containers

Bags & Bottles

Bracket

Any form, such as stands, carts, trays, etc.

Filling accuracy

±1%

*To ensure filling accuracy, the weighing unit accuracy should be better than 0.5% in the weighing filling mode, and the flow meter accuracy should be better than 0.5% in the flow rate filling mode.

Maximum processes / cycle

10 +1 (Exhaust and Purge)

Integrated peristaltic pump maximum flowrate

3.4 L/min

Single-use pressure sensor

0-60 PSI, precision better than 5%

Clamp-on flowmeter

0-15 L/min, precision better than 3%

Printer

Thermal non-adhesive printer

RJ45 interface

2

Weighting signal input

Any weighing unit supporting serial interface transmission

System control module

Siemens PLC

HMI

13-inch multi-touch industrial computer

Operation method

Finger touch/active stylus/VNC remote operation

Data storage

Encrypted database, storage capacity ≥10 years

Authorization

9-level user management, customizable user group authorization

Domain account management

Yes

Audit trail

Yes

Electronic signature

Yes

Recipe management

Yes

Online calibration

Yes

Batch management

Yes

Alarm and interlock

Yes

Online backup and recovery

Yes

Scheduled backup

Yes

Scada protocol

OPCUA, Modbus TCP/IP

Report generation

PDF

Language

Chinese / English

Power supply

90-260V AC 50/60Hz 2kW

Utility

No need for compressed air/purified water/water for injection

 

Ordering Information:

Model

Product number

Configuration

Standard version

DuoFill-A-10

Standard main controller x1, mixer base x1, bottle/bag tray x1

Upgraded version

DuoFill-B-10

Upgraded main controller x1, mixer base x1, bottle/bag tray x1

 

 



Relevant Documents

Contact Us
  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
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