久久久精品欧美一区二区三区,国产欧美久久久精品影院,亚洲AV福利天堂一区二区三亚洲欧洲日韩国产AⅤ在线,亚洲成av人在线视,四虎国产精品永久地址99自拍三区一级国产片,亚洲男人的天堂久久无在线观看免费黄视频,亚洲一级特黄大片在线播放,国产成人精品区在线观看

MixQ Mixed Mode Resin
Home > Technology > Chromatography Resin > MixQ Mixed Mode Resin > Mixed Mode Cation Chromatography Resin

Mixed Mode Cation Chromatography Resin


"Hard gel" mixed-mode cation chromatography resin MMC uses polymethacrylate as the matrix. Different from traditional agarose-based resin, "hard gel" MMC exhibits stronger pressure resistance and is particularly suitable for processing high viscosity and high turbidity samples. Through flexible hydrophilic technology, it not only retains the rigid characteristics of the polymer, but also has the good biocompatibility of agarose. In addition, we have launched a series of ultra-large pore (GP) products on this basis, specifically for the purification of macromolecules >100 kD or other ultra-large molecules.

 

Mixed Mode Cation Chromatography Resin

Figure 1 SEM pictures of chromatography resin with different pore sizes (Left: HP; Right: GP)

 

Capacity

 

The unique ligands of "hard gel" MMC not only cover conventional weak cationic functional groups, but also incorporate hydrophobic groups with benzene ring structures. Due to the combination of ion exchange and hydrophobic interaction, the MMC mixed mode weak cation exchange resin can maintain an ideal dynamic loading capacity even in a high-salt environment (see Figure 2).

Mixed Mode Cation Chromatography Resin

Figure 2 Comparison of capacities of MMC mixed mode weak cation exchange resins under different salt concentrations

 

Specification

 

Different series of MMC with different pore sizes assist your purification and provide you with the best choice.

Parameter

Specification

Product name

HPMMC-60

mixed mode weak cation exchange resin

GPMMC-60

mixed mode weak cation exchange resin

Pore size

30 nm

500 nm

Matrix

Polymethacrylate

Functional group

phenyl   (-C6H5), carboxyl (-COO)

Functional group type

Mixed mode weak cation

Max pressure

1 MPa

pH stability

pH 3-13

Storage

4 – 30 ℃(20% ethanol)

 

Applications

 

"Hard gel" MMC can effectively remove aggregates, nucleic acids, host proteins, viruses, and is widely used in purification in various fields, including the purification of recombinant subunit proteins, vaccines (including human vaccines and veterinary vaccines), collagen, and others.


Different target molecules correspond to different application scenarios, and a variety of MMC types are available. When the viscosity of the feed solution is high, it is recommended to choose a polymer matrix. See Figure 3 for detailed selection guide.


Mixed Mode Cation Chromatography Resin

Figure 3 MMC mixed mode weak cation exchange resin selection guide

 

The recombinant protein sample in the case in Figure 4 has high viscosity and high conductivity (>20 mS/cm). Conventional ion exchange chromatography requires dilution and diafiltration. However, MMC mixed mode weak cation exchange resin was used later to conduct pH and conductivity-based elution. The experimental results showed that impurities such as nucleic acid and HCP flowed through, and the purity of the eluted sample was >90%.

 

Mixed Mode Cation Chromatography Resin

Figure 4 Case study of recombinant protein purification using MMC mixed mode weak cation exchange resin

 

Polymer hard gel matrix (HP, GP) series ordering information:

Product name

Product number

Specification

MMC mixed mode weak cation exchange resin

(HPMMC-60)

BG66-1110-02

50 mL

BG66-1110-04

500 mL

BG66-1110-05

1 L

BG66-1110-07

10 L

BG66-1110-08

20 L

MMC mixed mode weak cation exchange resin

(GPMMC-60)

BG66-3110-02

50 mL

BG66-3110-04

500 mL

BG66-3110-05

1 L

BG66-3110-07

10 L

BG66-3110-08

20 L

 

 



Contact Us
  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
Message

Copyright ? Shanghai Duoning Biotechnology Co., Ltd. All Rights Reserved Sitemap | Technical Support: Reanod

WeChat
WeChat

Message-

Duoning Biotechnology

+86 021 6434 0155

国产亚洲欧美另类一区二区三区| 人妻无码熟妇乱又伦精品视频| 欧美日韩激情无码专区| 91尤物在线观看免费 | 中文字幕亚洲乱码熟女一区二区| 被公侵犯玩弄漂亮人妻中文| 亚洲国产精品成人综合| 国产成人精品亚洲日本专区61| 日本工口里番无遮█彩色| 亚洲ⅴ国产v天堂a无码二区| 黄色网页在线播放| 亚洲AV无码成人精品区在线播放| 国产区精品系列在线观看不卡| 亚洲欧洲日韩国产精品妖精| 四虎成人永久在线精品免费| 99久久精品国产免看国产一区| 成人va在线一区二区三区四区| 日本精品精品一二区一本到| 热RE99久久6国产精品免费| 中文字幕乱码一区二区三区免费| 99国产精品久久久久久久成人热| 77色午夜成人影院综合网| 国产真实强伦姧在线观看| 亚洲欧洲日产国码无码久久99| 久久精品女人18国产毛片蜜桃| 免费看的黄色视频一本无码| 亚洲人成欧美中文字幕| 93精91精品国产综合久久香蕉| 欧美黑人日韩三级破处女视频污片| 久久精品女人天堂AV麻| 久久99精品国产99久久| 国产精品美女久久久久| 最近中文字幕在线中文视频| 一级片免费观看视频| 久久人人爽人人爽人人AV东京热| 天天日天天插欧美日韩手机在线| 久久精品99久久香蕉国产| ,欧美日韩永久免费看看视频| 久久久久久久国产亚洲日本| 波多野结衣一区二区无码中文字幕| 亚洲AV成人WWW永久无码精品|