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Suspension Cell Culture
Home > Technology > Bioreactor > Suspension Cell Culture > DuoBioX? Elite Series Benchtop Cell Culture Bioreactor

DuoBioX? Elite Series Benchtop Cell Culture Bioreactor


Duoning DuoBioX? Elite is a benchtop cell culture bioreactor system that supports dual culture modes. Users can quickly establish and develop cell culture processes ranging from 3 to 15 liters with this system, achieving process establishment, development, and optimization with a highly cost-effective investment. The DuoBioX? Elite system is ideal for the early development of cell culture processes in scientific research institutions or the biopharmaceutical industry.

 

                                              DuoBioX? Elite Series Benchtop Cell Culture Bioreactor

 

Design Concept

 

The Elite system fully complies with the technical performance requirements of bioreactors in the biopharmaceutical industry. The process software employs a user-friendly design language to facilitate easier operation. The system operates stably and reliably, occupies minimal space, and offers users options for both touch and mobile operation platforms.

 

Material of Construction

 

The stainless-steel parts of the tank body that comes into contact with the liquid is constructed from SUS316L stainless steel and is electropolished to create an inert surface that is easy to clean. The glass tank body is made of high-quality tempered borosilicate glass, while the sealing materials consist of EPDM, silicone, and other substances that comply with FDA requirements. The non-liquid contact parts are made from high-quality SUS304 stainless steel.

 

System Hardware

 

?   Various tank specifications are available, including 3L, 5L, 7L, 15L and more.

?   The software is powerful and capable of comprehensive control based on feedback, time, conditions, and script recipes, effectively meeting the user's stringent process requirements.

?   The operating system, developed on the WinCC industrial-grade architecture, complies with GMP and 21 CFR Part 11 regulations, making it suitable for use in industries such as pharmaceuticals and medical devices.

?   In addition to the fundamental parameters of dissolved oxygen (DO), pH, temperature, liquid level, and stirring control units, the system can accommodate up to three ventilation gas pathways: surface ventilation, macro sparger bottom ventilation, and micro sparger bottom ventilation. This flexibility allows users to implement diverse and adaptable ventilation strategies, effectively supporting high-density perfusion culture processes. Furthermore, the optimized exhaust gas cooling device significantly reduces the risk of exhaust gas filter blockage and is compatible with both fermentation and high-density cell culture applications.

?   The controller is designed with additional input interfaces to connect sensors, such as those for cell density, CO2 levels, and weighing. It can also accommodate additional sensors in the control feedback system.


DuoBioX? Elite Series Benchtop Cell Culture Bioreactor


Model

Elite 500mL

Elite 3L

Elite 7L

Elite 15L

Function

Cell culture type, 1 control 1 or 1 control 2 (optional)

Tank body

Working volume

400 mL

2 L

5 L

10 L

Total volume

500 mL

3.1 L

6.8 L

15 L

Min. working volume

100 mL

0.6 L

1.5 L

3.2 L

H-to-D ratio

2:1

1.9:1

2.2:1

2.0:1

Np value

1.5

1.5

1.5

1.5

Impeller

3 inclined blades 45°

3 inclined blades 45°

3 inclined blades 45°

3 inclined blades 45°

Impeller diameter

35 mm

45 mm

60 mm

75 mm

Vent pipe diameter

4 mm

6 mm

8 mm

8 mm

Macro sparger pore size

0.5 mm

1 mm

1 mm

1 mm

Number of macro spargers

3

5

7

7

Micro sparger pore size

None

Optional

Optional

Optional

Controller

pH sensor

Gel  / 120

Gel / 225

Gel  / 325

Gel / 325

DO sensor

243666-112/120

(Optical) H2

243666-132/225

(Optical) H2

243666-142/325

(Optical) H2

243666-142/325

(Optical) H2

CO2 sensor

Optional

Optional

Optional

Optional

Overlay vent

Rotor flow meter

Rotor flow meter

Rotor flow meter

Rotor flow meter

MFC-Air

0~0.1 L

0~0.5 L

0~1 L

0~2 L

MFC-O2

0~0.1 L

0~0.5 L

0~1 L

0~2 L

MFC-CO2

0~0.1 L

0~0.5 L

0~0.5 L

0~1 L

MFC-N2

Optional

Optional

Optional

Optional

MFC-O2 micro sparger

0~0.1 Optional

0~0.1 Optional

0~0.5 Optional

0~1 Optional

Built-in peristaltic pump

4x built-in, viable speed

4x built-in, viable speed

4x built-in, viable speed

4x built-in, viable speed

Temperature control

Electric heating base 100w

Cooling water solenoid valve

Electric heating blanket 400w

Cooling water solenoid valve

Electric heating blanket 400w

Cooling water solenoid valve

Electric heating blanket 400w

Cooling water solenoid valve

Exhaust gas condensation

None

Semiconductor or water cooling

Semiconductor or water cooling

Semiconductor or water cooling

Weighting

Optional

Optional

Optional

Optional

Control software (needs to be installed on the user's computer)

21 CFR Part 11

Yes

Yes

Yes

Yes

Data records

Yes

Yes

Yes

Yes

User authorization management

4 levels

4 levels

4 levels

4 levels

Utility requirements

Air source

Air, O2, CO2

Air,  O2, CO2

Air, O2, CO2

Air,  O2, CO2

Air source pressure

0.2-0.3 MPa

0.2-0.3 MPa

0.2-0.3 MPa

0.2-0.3 MPa

Control cabinet power supply

220 v 50 Hz

220 v 50 Hz

220 v 50 Hz

220 v 50 Hz

Power socket

10A three-hole

10A three-hole

10A three-hole

10A three-hole

Control cabinet dimension

Depth*Width*Height 520*350*618 mm

Depth*Width*Height 520*350*618 mm

Depth*Width*Height 520*350*618 mm

Depth*Width*Height   520*350*618 mm

External dimensions of a single tank (w/o exhaust condenser)

Height*Diameter 357*100 mm

Height*Diameter 410*210 mm

Height*Diameter 520*250 mm

Height*Diameter 620*280 mm

Control cabinet net weight

35 kg

35 kg

35 kg

35 kg

Tank net weight

2 kg

8 kg

11 kg

15 kg


Contact Us
  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
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